  The Woodlands, TX  My mom was diagnosed with breast cancer while I was in high school and I became interested in the links between environment (especially nutrition), metabolism, and health. My honours project at McGill University, Montreal, Quebec (Biology Honours) dealt with folic acid metabolism, genetically induced folic acid deficiency, dietary supplementation, and their effects on placental development in mice.  6th year. Ph.D. Candidate. Working on finishing my dissertation on mechanisms behind the effects and benefits of caloric restriction, and hematopoietic stem cell aging and function.  cooking, hiking, or anything to enjoy the California outdoors, and having inspiring conversations with the other graduate students I live with in the BSC co-op. Going out for a drink with friends is also nice... |
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Publications
Brown K*, Liu Y*, Chen D (2012). Aging: the Mitochondrial Connection. J Clin Exp Pathol. S4:003. (*These authors contributed equally)
Brown K*, Qiu X*, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 2010 Dec 1;12(6):662-7. (*These authors contributed equally)
Qiu X, Brown KV, Moran Y, Chen D. Sirtuin regulation in calorie restriction. Biochim Biophys Acta. 2010 Aug;1804(8):1576-83.
Pickell L, Brown K, Li D, Wang XL, Deng L, Wu Q, Selhub J, Luo L, Jerome-Majewska L, Rozen R. High intake of folic acid disrupts embryonic development in mice. Birth Defects Res A Clin Mol Teratol. 2011 Jan;91(1):8-19.
Pickell L, Li D, Brown K, Mikael LG, Wang XL, Wu Q, Luo L, Jerome-Majewska L, Rozen R. Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice. Birth Defects Res A Clin Mol Teratol. 2009 Jun;85(6):531-41.