Speaker: Lene Juel Rasmussen, Professor, University of Copenhagen, Denmark

The pursuit of understanding the molecular mechanisms underlying human longevity has emerged as a central focus in biomedical research, driven by the challenges posed by an aging global population. In this presentation, I will explore recent advancements in the identification and characterization of human longevity genes, shedding light on the complex interplay between genetic factors and lifespan regulation.

The discussion will center on the functional analysis of a newly discovered longevity gene OSER1. Our findings provide valuable insights into the gene's role in fundamental cellular processes, including oxidative stress response, cellular senescence, and mitochondrial function. Additionally, I will highlight the potential therapeutic implications of this research, emphasizing innovative strategies and interventions designed to modulate the expression or activity of longevity genes. These approaches hold promise for promoting healthy aging and delaying the onset of age-related diseases.